Which of the following is an Orange Book rating?

The correct answer is B. The Orange Book, officially known as the "Approved Drug Products with Therapeutic Equivalence Evaluations," utilizes a system of ratings to indicate the therapeutic equivalence of pharmaceutical products.

A rating starting with the letter "B" designates that the products are considered to be therapeutically equivalent to other products in the same category. This means that a drug labeled with a "B" rating may be substituted for another brand or generic drug without concern for efficacy or safety differences. Typically, these products have met certain necessary standards and are deemed interchangeable.

On the other hand, you may encounter ratings like "A" which signify that the products are therapeutically equivalent. However, "AZ" and "BZ" include specific designations related to certain conditions and might not imply direct equivalence. Similarly, "CZ" is not a recognized rating in the context of the Orange Book. Therefore, only the "B" rating denotes the general acceptability for therapeutic equivalence in substitution scenarios. Understanding these ratings is essential for pharmaceutical representatives as it impacts formulary decisions and medication dispensing.