Which is not a recognized route of drug administration?

The correct answer is based on the fact that "transfugal" is not a recognized route of drug administration. In the context of pharmaceutical education, understanding the various routes of administration is essential.

Buccal administration involves placing a drug between the gums and the inner lining of the cheek, allowing it to be absorbed into the bloodstream through the tissues in the mouth. This method is effective for certain medications as it bypasses the digestive system and first-pass metabolism.

Intramuscular administration entails injecting the drug directly into a muscle, allowing for rapid absorption due to the rich blood supply in muscle tissue. This route is commonly utilized for vaccines and certain medications that require quicker onset than oral administration.

Sublingual administration involves placing a drug under the tongue, where it dissolves and is absorbed directly into the bloodstream. This route is advantageous for drugs that would be degraded by the gastrointestinal tract or would have a significant first-pass effect if taken orally.

In contrast, "transfugal" does not correspond to any standard method of drug delivery recognized in medical or pharmaceutical texts. Understanding these recognized routes helps professionals choose the most appropriate method for delivering medications to ensure efficacy and safety.